Somatostatin: The Pancreatic Hormone
What is Somatostatin?
Somatostatin is a naturally occurring hormone produced in several parts of the body, including the pancreas, hypothalamus, and gastrointestinal tract. In the pancreas, it is secreted by delta cells and plays a key role in regulating digestion, metabolism, and hormone secretion.
Functions of Somatostatin
Dr. Pavan K Addala explains that somatostatin acts as a “brake” for several body processes:
- Regulates Hormones: Inhibits insulin, glucagon, and growth hormone release.
- Controls Digestion: Reduces the secretion of gastric acid, pancreatic enzymes, and bile.
- Slows Gastrointestinal Motility: Helps prevent rapid emptying of food from the stomach.
- Balances Blood Sugar: Prevents excessive swings in glucose levels.
Disorders Related to Somatostatin
- Somatostatinoma: A rare pancreatic neuroendocrine tumour that produces excess somatostatin.
- Hormonal Imbalance: Low levels can lead to overproduction of insulin or glucagon.
- Digestive Disorders: Abnormal somatostatin function can affect nutrient absorption.
Somatostatin in Medicine
Synthetic forms of somatostatin (like octreotide) are used in treating:
- Pancreatitis
- Variceal bleeding in the esophagus
- Hormone-secreting tumours
Expert Care in Hyderabad
If you have symptoms like unexplained diarrhoea, diabetes with fluctuating sugar levels, or digestive issues, it’s important to consult a specialist.
Dr. Pavan K Addala, a leading gastroenterologist in Hyderabad, specialises in diagnosing and managing pancreatic disorders, hormone-related conditions, and digestive diseases.
